Bavachin protects against diet-induced hepatic steatosis and
WEBJan 31, 2023 · Recent evidence shows that bavachin, a flavonoid isolated from the seeds and fruits of Psoralea corylifolia L., increases the transcriptional activity of PPARγ and insulin sensitivity during ...
Bavachin induces liver injury and cell apoptosis by targeting …
WEBSep 15, 2023 · Bavachin, a flavonoid compound isolated from the fruits of Psoralea corylifolia L., has been validated to induce direct apoptosis in hepatocytes and liver tissues in our previous studies. However, the subcellular mechanisms of bavachin induced liver injury is still elusive.
Bavachin | C20H20O4 | CID 14236566 - PubChem
WEBBavachin | C20H20O4 | CID 14236566 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Bavachin protects against diet-induced hepatic steatosis and
WEBRecent evidence shows that bavachin, a flavonoid isolated from the seeds and fruits of Psoralea corylifolia L., increases the transcriptional activity of PPARγ and insulin sensitivity during preadipocyte differentiation, but the effect of bavachin on glucose and lipid metabolism remains unclear.
Bavachin Protects Human Aortic Smooth Muscle Cells Against
WEBDec 19, 2019 · Bavachin, a natural compound from Psoralea corylifolia, dose-dependently reduced the level of intracellular calcium and the expression of calcification-related proteins OPG, OPN, Runx2 and BMP2, thus inhibiting cell apoptosis.
Neuroprotective effects of bavachin against neuroinflammation …
WEBAug 1, 2023 · Bavachin is a flavonoid compound in Psoralea corylifolia, which has multiple biological activities, however its neuroprotective effect and molecular mechanism remain unclear. We found that bavachin inhibited neuroinflammation and also exerted significant antioxidative stress effects.
Bavachin protects against diet-induced hepatic steatosis and …
WEBJan 31, 2023 · Bavachin is a bioactive natural flavonoid widely used in traditional medicine and is isolated from the seeds and fruits of Psoralea corylifolia L . Bavachin has been reported to have anti-tumor, anti-oxidant, anti-inflammatory, immunomodulatory, and estrogenic activities .
Characterization of metabolic activity, isozyme contribution and ...
WEBBavachin is a bioactive natural flavonoid with oestrogen-like activity. Here, we aimed to investigate its metabolic and disposal fates involving in CYPs, UGTs and efflux transporters. Methods. Phase I metabolism and glucuronidation were performed by human liver microsomes (HLM).
Bavachin Protects Human Aortic Smooth Muscle Cells Against
WEBDec 19, 2019 · Bavachin, a natural compound from Psoralea corylifolia, dose-dependently reduced the level of intracellular calcium and the expression of calcification-related proteins OPG, OPN, Runx2 and BMP2, thus inhibiting cell apoptosis.
Bavachin induces liver injury and cell apoptosis by targeting …
WEBSep 15, 2023 · Bavachin, a flavonoid compound isolated from the fruits of Psoralea corylifolia L., has been validated to induce direct apoptosis in hepatocytes and liver tissues in our previous studies. However, the subcellular mechanisms of bavachin induced liver injury is still elusive.