Mechanisms underlying the effect of voluntary running on adult …
WEBVoluntary running promotes exit of neural stem cells (NSCs) from the quiescent stage, proliferation of NSCs and progenitors, survival of newborn cells, morphological development of immature neuron, and integration of new neurons into the hippocampal circuitry.
Voluntary running does not reduce neuroinflammation or …
WEBJan 28, 2020 · We investigated the effects of 24 weeks of voluntary wheel running in female 5xFAD mice (n = 30) starting at 2–3 months of age, before substantial extracellular plaque formation.
Mechanisms underlying the effect of voluntary running on adult ...
WEBVoluntary running promotes exit of neural stem cells (NSCs) from the quiescent stage, proliferation of NSCs and progenitors, survival of newborn cells, morphological development of immature neuron, and integration of new neurons into the hippocampal circuitry.
Orexin neurons mediate temptation-resistant voluntary exercise
WEBAug 6, 2024 · Orexin neurons mediate temptation-resistant voluntary exercise. Alexander L. Tesmer, Xinyang Li, Eva Bracey, Cyra Schmandt, Rafael Polania, Daria Peleg-Raibstein & Denis Burdakov. Nature...
Exercise enhances motor skill learning by neurotransmitter ... - Nature
WEBMay 4, 2020 · We find that one week of voluntary wheel running enhances the acquisition of motor skills in normal adult mice. One week of running also induces switching from ACh to GABA expression in neurons...
Voluntary wheel running: patterns and physiological effects in …
WEBDec 10, 2018 · Mice run spontaneously when given access to running wheels, for a total distance of ∼4 to 20 km per day and a total activity time of ∼3 to 7 hours a day. Hence, voluntary wheel running can result in robust endurance-like adaptation in skeletal and cardiac muscles and protect from sarcopenia.
RGS6 mediates effects of voluntary running on adult …
WEBAug 4, 2020 · RGS6 overexpression mimics the positive effects of voluntary running on morphological and physiological maturation of adult new neurons and reduced sensitivity of adult-born neurons to inhibitory effect of GABA B receptor activation.
Voluntary running protects against neuromuscular dysfunction following ...
WEBJan 1, 2019 · NEW & NOTEWORTHY This work provides the first evidence that preemptive voluntary wheel running reduces neuromuscular dysfunction following ischemia-reperfusion injury in skeletal muscle. These findings may alter clinical practices in which a tourniquet is used to modulate blood flow.
Voluntary running protects against neuromuscular dysfunction following ...
WEBJan 29, 2019 · This work provides the first evidence that preemptive voluntary wheel running reduces neuromuscular dysfunction following ischemia-reperfusion injury in skeletal muscle. These findings may alter cl...
Running Changes the Brain: the Long and the Short of It
WEBOct 11, 2017 · Altogether, our recent findings show that adult-born neurons have unique anatomical and physiological properties that can be continuously changed by voluntary running from the progenitor cell stage throughout the process of integration into the hippocampal circuitry.
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