Lysosomes are critical for cellular degradation, characterized by their acidic pH and array of hydrolytic enzymes. They degrade materials through endocytosis, phagocytosis, and autophagy ...

All modern multicellular life — all life that any of us regularly see — is made of cells with a knack for ...

The microglia, in turn, seem to benefit, revving up metabolism and phagocytosis. The liver protein ApoA-I was particularly good at bolstering the latter. Overall, the findings suggest that the brain’s ...

Cell biologists have been intrigued by endocytosis ever since Ilya Metchnikoff described the phenomenon of phagocytosis ... in intracellular vacuoles and lysosomes. Using microscopy and ...

Entotic cell killing involves autophagy proteins that facilitate lysosome fusion to the endosomes surrounding engulfed cells, an activity that is part of an emerging field of non-canonical autophagy ...

Lipids Open the Door. Microglial cells treated with unlipidated (top) or lipidated (bottom) ApoE (yellow) along with fluorescently tagged Aβ (green). Lipidated ApoE was more readily internalized and ...

As a result, tuftsin possesses a broad spectrum of activities primarily related to the immune system function, which includes potentiation of phagocytosis, immunogenic response and bactericidal ...