This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

Interest in lysosomal storage diseases (LSDs) has increased significantly ... outlined the ability of Myozyme (Genzyme), recombinant human α-glucosidase, to increase survival in afflicted ...

This breakthrough could eventually lead to treatments for diseases like frontotemporal ... is a phospholipid that is located in lysosomes—the cell's garbage bins. "BMP is a co-factor for ...

Two of them - mitochondria and lysosomes - help to respectively ... that preventing senescence may counteract human ageing ...

These observations open the door to more in-depth investigations looking into a potential mechanistic link between TMEM106b aggregation and pathological processes in neurodegeneration,” Rothstein ...

Lipids Open the Door. Microglial cells treated with unlipidated (top) or lipidated (bottom) ApoE (yellow) along with fluorescently tagged Aβ (green). Lipidated ApoE was more readily internalized and ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" ...

Researchers found that traumatic brain injury increases synaptic dysfunction and cognitive impairments linked to developing Alzheimer's disease. Study: Neuronal BAG3 attenuates tau ...

COLUMBUS, Ohio – Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer’s disease later in life. Researchers ...

Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer's disease later ... mouse models and human post-mortem ...

Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk of ...