De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...

This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous with one another. Therefore, the membrane lipids and proteins that are synthesized in ...

In a breakthrough that could eventually lead to new treatments for devastating conditions like Alzheimer’s disease, ...

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

A preclinical University of Toronto study is revealing new insights into the molecular machinery that drives the aggressiveness of pancreatic cancer. This cancer’s ability to invade and spread to ...

This chemical, when consumed, causes cell death/degeneration as it attacks the membrane of lysosomes. The olive oil you’re using may be fake In a Sydney Diet-Heart Study, they found that participants ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" ...

Lipids Open the Door. Microglial cells treated with unlipidated (top) or lipidated (bottom) ApoE (yellow) along with fluorescently tagged Aβ (green). Lipidated ApoE was more readily internalized and ...

Stress granules (SGs) form in response to diverse environmental signals. Here, the signaling pathways that connect lysosomal ...

Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...