Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The San Diego Padres (88-66) will host the Chicago White Sox (36-118), Saturday at 8:40 p.m. ET, with the White Sox on a ...

Chicago White Sox (36-118, fifth in the AL Central) vs. San Diego Padres (88-66, second in the NL West) San Diego; Saturday, ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

The Chicago White Sox fought valiantly on Friday night, but still suffered a late loss against the San Diego Padres. With ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

ET, Jurickson Profar and the San Diego Padres (88-66) face Andrew Vaughn and the Chicago White Sox (36-118) at PETCO Park.

The Chicago White Sox trailed by two runs as Sosa batted with a runner on and two outs in the ninth inning against the San Diego Padres at Petco Park. After a ball, Sosa fouled off the next three ...

White sox ninth. Andrew Benintendi strikes out swinging. Andrew Vaughn grounds out to shortstop, Xander Bogaerts to Donovan Solano. Gavin Sheets walks. Lenyn Sosa homers to center field. Gavin Sheets ...

Fernando Tatis Jr.'s walkoff double in the 10th inning helped the Friars open their final home (regular season) series of the ...